Blocking Gi/o-Coupled Signaling Eradicates Cancer Stem Cells and Sensitizes Breast Tumors to HER2-Targeted Therapies to Inhibit Tumor Relapse

SIMPLE SUMMARY: Cancer stem cells (CSCs) are associated with therapeutic resistance and tumor relapse but effective approaches for eliminating CSCs are still lacking. The aim of this study was to assess the role of G protein-coupled receptors (GPCRs) in regulating CSCs in breast cancer. We showed th...

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Detalles Bibliográficos
Autores principales: Lyu, Cancan, Ye, Yuanchao, Weigel, Ronald J., Chen, Songhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997047/
https://www.ncbi.nlm.nih.gov/pubmed/35406489
http://dx.doi.org/10.3390/cancers14071719

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997047/
https://www.ncbi.nlm.nih.gov/pubmed/35406489
http://dx.doi.org/10.3390/cancers14071719

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