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HPV8 Reverses the Transcriptional Output in Lrig1 Positive Cells to Drive Skin Tumorigenesis

SIMPLE SUMMARY: Human papillomavirus (HPV) of genus beta (betaHPV) infects cutaneous epithelia and contributes to skin carcinogenesis, particularly in immunosuppressed patients. The HPV8 transgenic mouse model serves as a model for betaHPV-induced skin tumorigenesis. These animals express the comple...

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Detalles Bibliográficos
Autores principales: Syed, Adnan Shahzad, Marcuzzi, Gian Paolo, Miller-Lazic, Daliborka, Hess, Jochen, Hufbauer, Martin, Akgül, Baki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997052/
https://www.ncbi.nlm.nih.gov/pubmed/35406439
http://dx.doi.org/10.3390/cancers14071662