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Inhibiting the Priming for Cancer in Li-Fraumeni Syndrome

SIMPLE SUMMARY: Li-Fraumeni Syndrome (LFS) is a rare cancer pre-disposition syndrome associated with a germline mutation in the TP53 tumour suppressor gene. People with LFS have a 90% chance of suffering one or more cancers in their lifetime. No treatments exist to reduce this cancer risk. This pape...

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Detalles Bibliográficos
Autores principales: Pantziarka, Pan, Blagden, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997074/
https://www.ncbi.nlm.nih.gov/pubmed/35406393
http://dx.doi.org/10.3390/cancers14071621