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TGF-β/SMAD Pathway Is Modulated by miR-26b-5p: Another Piece in the Puzzle of Chronic Lymphocytic Leukemia Progression

SIMPLE SUMMARY: TGF-β is a key immunoregulatory pathway that can limit the proliferation of B-lymphocytes. Chronic lymphocytic leukemia (CLL) has been historically conceptualized as a neoplasm characterized by accumulation of mature B cells escaping programmed cell death and undergoing cell-cycle ar...

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Detalles Bibliográficos
Autores principales: Marquez, Maria Elena, Sernbo, Sandra, Payque, Eugenia, Uria, Rita, Tosar, Juan Pablo, Querol, Juliana, Berca, Catalina, Uriepero, Angimar, Prieto, Daniel, Alvarez-Saravia, Diego, Oliver, Carolina, Irigoin, Victoria, Dos Santos, Gimena, Guillermo, Cecilia, Landoni, Ana Inés, Navarrete, Marcelo, Palacios, Florencia, Oppezzo, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997107/
https://www.ncbi.nlm.nih.gov/pubmed/35406446
http://dx.doi.org/10.3390/cancers14071676