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Cell Type-Specific Roles of STAT3 Signaling in the Pathogenesis and Progression of K-ras Mutant Lung Adenocarcinoma

SIMPLE SUMMARY: Lung adenocarcinomas with mutations in the K-ras gene are hard to target pharmacologically and highly lethal. As a result, there is a need to identify other therapeutic targets that influence K-ras oncogenesis. One contender is STAT3, a transcription factor that is associated with K-...

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Detalles Bibliográficos
Autores principales: Clowers, Michael J., Moghaddam, Seyed Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997152/
https://www.ncbi.nlm.nih.gov/pubmed/35406557
http://dx.doi.org/10.3390/cancers14071785