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Hepatic PPARα Is Destabilized by SIRT1 Deacetylase in Undernourished Male Mice

The nutrient sensing nuclear receptor peroxisome proliferator-activated receptor-α (PPARα) regulates the host response to short-term fasting by inducing hepatic transcriptional programming of ketogenesis, fatty acid oxidation and transport, and autophagy. This adaptation is ineffective in chronicall...

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Detalles Bibliográficos
Autores principales:	Suh, Ji Ho, Kim, Kang Ho, Conner, Margaret E., Moore, David D., Preidis, Geoffrey A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Nutrition
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997242/ https://www.ncbi.nlm.nih.gov/pubmed/35419389 http://dx.doi.org/10.3389/fnut.2022.831879

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