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ZNF768: controlling cellular senescence and proliferation with ten fingers

We recently identified Zinc-finger protein 768 (ZNF768) as a novel transcription factor controlling cell fate decision downstream of Rat sarcoma virus (RAS). We showed that ZNF768 depletion impairs cell cycle progression and triggers cellular senescence, while its overexpression allows cells to bypa...

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Detalles Bibliográficos
Autores principales: Villot, Romain, Poirier, Audrey, Devillers, Romain, Kolnoguz, Aliona, Elowe, Sabine, Manem, Venkata S. K., Joubert, Philippe, Mallette, Frédérick A., Laplante, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997246/
https://www.ncbi.nlm.nih.gov/pubmed/35419475
http://dx.doi.org/10.1080/23723556.2021.1985930