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Pan-human consensus genome significantly improves the accuracy of RNA-seq analyses

The Human Reference Genome serves as the foundation for modern genomic analyses. However, in its present form, it does not adequately represent the vast genetic diversity of the human population. In this study, we explored the consensus genome as a potential successor of the current reference genome...

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Detalles Bibliográficos
Autores principales: Kaminow, Benjamin, Ballouz, Sara, Gillis, Jesse, Dobin, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997357/
https://www.ncbi.nlm.nih.gov/pubmed/35256454
http://dx.doi.org/10.1101/gr.275613.121