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The role of insulators and transcription in 3D chromatin organization of flies

The DNA in many organisms, including humans, is shown to be organized in topologically associating domains (TADs). In Drosophila, several architectural proteins are enriched at TAD borders, but it is still unclear whether these proteins play a functional role in the formation and maintenance of TADs...

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Detalles Bibliográficos
Autores principales: Chathoth, Keerthi T., Mikheeva, Liudmila A., Crevel, Gilles, Wolfe, Jareth C., Hunter, Ioni, Beckett-Doyle, Saskia, Cotterill, Sue, Dai, Hongsheng, Harrison, Andrew, Zabet, Nicolae Radu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997359/
https://www.ncbi.nlm.nih.gov/pubmed/35354608
http://dx.doi.org/10.1101/gr.275809.121