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GC content, but not nucleosome positioning, directly contributes to intron splicing efficiency in Paramecium

Eukaryotic genes are interrupted by introns that must be accurately spliced from mRNA precursors. With an average length of 25 nt, the more than 90,000 introns of Paramecium tetraurelia stand among the shortest introns reported in eukaryotes. The mechanisms specifying the correct recognition of thes...

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Detalles Bibliográficos
Autores principales: Gnan, Stefano, Matelot, Mélody, Weiman, Marion, Arnaiz, Olivier, Guérin, Frédéric, Sperling, Linda, Bétermier, Mireille, Thermes, Claude, Chen, Chun-Long, Duharcourt, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997360/
https://www.ncbi.nlm.nih.gov/pubmed/35264448
http://dx.doi.org/10.1101/gr.276125.121