Perspective on the Use of DNA Repair Inhibitors as a Tool for Imaging and Radionuclide Therapy of Glioblastoma

SIMPLE SUMMARY: The current routine treatment for glioblastoma (GB), the most lethal high-grade brain tumor in adults, aims to induce DNA damage in the tumor. However, the tumor cells might be able to repair that damage, which leads to therapy resistance. Fortunately, DNA repair defects are common i...

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Detalles Bibliográficos
Autores principales: Everix, Liesbeth, Nair, Shankari, Driver, Cathryn H. S., Goethals, Ingeborg, Sathekge, Mike M., Ebenhan, Thomas, Vandevoorde, Charlot, Bolcaen, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997380/
https://www.ncbi.nlm.nih.gov/pubmed/35406593
http://dx.doi.org/10.3390/cancers14071821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997380/
https://www.ncbi.nlm.nih.gov/pubmed/35406593
http://dx.doi.org/10.3390/cancers14071821

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