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Targeting GLI1 Transcription Factor for Restoring Iodine Avidity with Redifferentiation in Radioactive-Iodine Refractory Thyroid Cancers

SIMPLE SUMMARY: Thyroid cancers have an excellent prognosis by standard therapy of surgery followed by radioactive-iodine therapy. However, metastatic thyroid cancers do not response to radioactive-iodine therapy by losing iodine avidity. Therefore, reversing iodine avidity to metastatic thyroid can...

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Detalles Bibliográficos
Autores principales: Oh, Ji Min, Rajendran, Ramya Lakshmi, Gangadaran, Prakash, Hong, Chae Moon, Jeong, Ju Hye, Lee, Jaetae, Ahn, Byeong-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997411/
https://www.ncbi.nlm.nih.gov/pubmed/35406554
http://dx.doi.org/10.3390/cancers14071782