Inflammatory Caspase Activity Mediates HMGB1 Release and Differentiation in Myoblasts Affected by Peripheral Arterial Disease

Introduction: We previously showed that caspase-1 and -11, which are activated by inflammasomes, mediate recovery from muscle ischemia in mice. We hypothesized that similar to murine models, inflammatory caspases modulate myogenicity and inflammation in ischemic muscle disease. Methods: Caspase acti...

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Detalles Bibliográficos
Autores principales: Ferrari, Ricardo, Xie, Bowen, Assaf, Edwyn, Morder, Kristin, Scott, Melanie, Liao, Hong, Calderon, Michael J., Ross, Mark, Loughran, Patricia, Watkins, Simon C., Pipinos, Iraklis, Casale, George, Tzeng, Edith, McEnaney, Ryan, Sachdev, Ulka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997414/
https://www.ncbi.nlm.nih.gov/pubmed/35406727
http://dx.doi.org/10.3390/cells11071163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997414/
https://www.ncbi.nlm.nih.gov/pubmed/35406727
http://dx.doi.org/10.3390/cells11071163

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