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Inflammatory Caspase Activity Mediates HMGB1 Release and Differentiation in Myoblasts Affected by Peripheral Arterial Disease
Introduction: We previously showed that caspase-1 and -11, which are activated by inflammasomes, mediate recovery from muscle ischemia in mice. We hypothesized that similar to murine models, inflammatory caspases modulate myogenicity and inflammation in ischemic muscle disease. Methods: Caspase acti...
Autores principales: | Ferrari, Ricardo, Xie, Bowen, Assaf, Edwyn, Morder, Kristin, Scott, Melanie, Liao, Hong, Calderon, Michael J., Ross, Mark, Loughran, Patricia, Watkins, Simon C., Pipinos, Iraklis, Casale, George, Tzeng, Edith, McEnaney, Ryan, Sachdev, Ulka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997414/ https://www.ncbi.nlm.nih.gov/pubmed/35406727 http://dx.doi.org/10.3390/cells11071163 |
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