A Heme-Binding Transcription Factor BACH1 Regulates Lactate Catabolism Suggesting a Combined Therapy for Triple-Negative Breast Cancer

The oncogenic expression or mutation of tumor suppressors drives metabolic alteration, causing cancer cells to utilize diverse nutrients. Lactate is a known substrate for cancer cells, yet the regulatory mechanisms of lactate catabolism are limited. Here, we show that a heme-binding transcription fa...

Descripción completa

Detalles Bibliográficos
Autores principales: Padilla, Joselyn, Lee, Bok-Soon, Zhai, Karen, Rentz, Bethany, Bobo, Tia, Dowling, Norca Maritza, Lee, Jiyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997507/
https://www.ncbi.nlm.nih.gov/pubmed/35406740
http://dx.doi.org/10.3390/cells11071177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997507/
https://www.ncbi.nlm.nih.gov/pubmed/35406740
http://dx.doi.org/10.3390/cells11071177

Ejemplares similares