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Suitability of Human Mesenchymal Stem Cells Derived from Fetal Umbilical Cord (Wharton’s Jelly) as an Alternative In Vitro Model for Acute Drug Toxicity Screening

Preclinical toxicity screening is the first and most crucial test that assesses the safety of new candidate drugs before their consideration for further evaluation in clinical trials. In vitro drug screening using stem cells has lately arisen as a promising alternative to the “gold standard” of anim...

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Detalles Bibliográficos
Autores principales: Christodoulou, Ioannis, Goulielmaki, Maria, Kritikos, Andreas, Zoumpourlis, Panagiotis, Koliakos, Georgios, Zoumpourlis, Vassilis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997545/
https://www.ncbi.nlm.nih.gov/pubmed/35406666
http://dx.doi.org/10.3390/cells11071102