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Conversion of Hyperpolarized [1-(13)C]Pyruvate in Breast Cancer Cells Depends on Their Malignancy, Metabolic Program and Nutrient Microenvironment

SIMPLE SUMMARY: The metabolic phenotype of cancer cells depends on their metabolic program and the availability of nutrients in the tumor microenvironment. Metabolic activities in vivo can be characterized by using magnetic resonance spectroscopy (MRS) for analyzing the conversion of hyperpolarized...

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Detalles Bibliográficos
Autores principales: Grashei, Martin, Biechl, Philipp, Schilling, Franz, Otto, Angela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997828/
https://www.ncbi.nlm.nih.gov/pubmed/35406616
http://dx.doi.org/10.3390/cancers14071845