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Transcriptomic Profiling of DNA Damage Response in Patient-Derived Glioblastoma Cells before and after Radiation and Temozolomide Treatment

Glioblastoma is a highly aggressive, invasive and treatment-resistant tumour. The DNA damage response (DDR) provides tumour cells with enhanced ability to activate cell cycle arrest and repair treatment-induced DNA damage. We studied the expression of DDR, its relationship with standard treatment re...

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Detalles Bibliográficos
Autores principales: Lozinski, Mathew, Bowden, Nikola A., Graves, Moira C., Fay, Michael, Day, Bryan W., Stringer, Brett W., Tooney, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997841/
https://www.ncbi.nlm.nih.gov/pubmed/35406779
http://dx.doi.org/10.3390/cells11071215