Serine Palmitoyltransferase Gene Silencing Prevents Ceramide Accumulation and Insulin Resistance in Muscles in Mice Fed a High-Fat Diet

Skeletal muscles account for ~80% of insulin-stimulated glucose uptake and play a key role in lipid metabolism. Consumption of a high-fat diet (HFD) contributes to metabolic changes in muscles, including the development of insulin resistance. The studies carried out to date indicate that the accumul...

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Detalles Bibliográficos
Autores principales: Imierska, Monika, Zabielski, Piotr, Roszczyc-Owsiejczuk, Kamila, Sokołowska, Emilia, Pogodzińska, Karolina, Kojta, Iwona, Błachnio-Zabielska, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997855/
https://www.ncbi.nlm.nih.gov/pubmed/35406688
http://dx.doi.org/10.3390/cells11071123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997855/
https://www.ncbi.nlm.nih.gov/pubmed/35406688
http://dx.doi.org/10.3390/cells11071123

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