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The Sin3A/MAD1 Complex, through Its PAH2 Domain, Acts as a Second Repressor of Retinoic Acid Receptor Beta Expression in Breast Cancer Cells

Retinoids are essential in balancing proliferation, differentiation and apoptosis, and they exert their effects through retinoic acid receptors (RARs) and retinoid X receptors (RXRs). RARβ is a tumor-suppressor gene silenced by epigenetic mechanisms such as DNA methylation in breast, cervical and no...

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Detalles Bibliográficos
Autores principales: Dahiya, Nisha Rani, Leibovitch, Boris A., Kadamb, Rama, Bansal, Nidhi, Waxman, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997856/
https://www.ncbi.nlm.nih.gov/pubmed/35406744
http://dx.doi.org/10.3390/cells11071179