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The Effect of Ex Vivo Human Serum from Liver Disease Patients on Cellular Protein Synthesis and Growth

Sarcopenia is a common complication affecting liver disease patients, yet the underlying mechanisms remain unclear. We aimed to elucidate the cellular mechanisms that drive sarcopenia progression using an in vitro model of liver disease. C2C12 myotubes were serum and amino acid starved for 1-h and s...

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Detalles Bibliográficos
Autores principales: Allen, Sophie L., Seabright, Alex P., Quinlan, Jonathan I., Dhaliwal, Amritpal, Williams, Felicity R., Fine, Nicholas H. F., Hodson, David J., Armstrong, Matthew J., Elsharkaway, Ahmed M., Greig, Carolyn A., Lai, Yu-Chiang, Lord, Janet M., Lavery, Gareth G., Breen, Leigh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997893/
https://www.ncbi.nlm.nih.gov/pubmed/35406665
http://dx.doi.org/10.3390/cells11071098