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Soft Tissue Sarcoma Study: Association of Genetic Alterations in the Apoptosis Pathways with Chemoresistance to Doxorubicin

SIMPLE SUMMARY: Genotoxic chemotherapy is the main component of the treatment for advanced soft tissue sarcomas. However, its efficacy is rather low and it is followed by rapid appearance of drug resistance. Our study was directed to the search of molecular drivers of chemoresistance in synovial and...

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Detalles Bibliográficos
Autores principales: Kirilin, Evgeny M., Fetisov, Timur I., Moiseeva, Natalia I., Lesovaya, Ekaterina A., Laletina, Lidia A., Makhmudova, Leyla F., Manikaylo, Angelika E., Fomina, Liliya Y., Burov, Denis A., Bokhyan, Beniamin Yu., Zinovieva, Victoria Y., Vilkova, Alice S., Mekheda, Larisa V., Kozlov, Nikolay A., Scherbakov, Alexander M., Belitsky, Gennady A., Švedas, Vytas, Kirsanov, Kirill I., Yakubovskaya, Marianna G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997914/
https://www.ncbi.nlm.nih.gov/pubmed/35406568
http://dx.doi.org/10.3390/cancers14071796