Complement Proteins C5/C5a, Cathepsin D and Prolactin in Chondrocytes: A Possible Crosstalk in the Pathogenesis of Osteoarthritis

Introduction: Both increased activity of the complement system (CS) and the role of the pituitary hormone prolactin (PRL) are implicated in osteoarthritis (OA) pathogenesis. Besides, Cathepsin D (CatD) activity is increased in the context of OA and can exert not only proteolytic but also non-proteol...

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Detalles Bibliográficos
Autores principales: Silawal, Sandeep, Wagner, Miriam, Roth, Dominik, Bertsch, Thomas, Schwarz, Silke, Willauschus, Maximilian, Gesslein, Markus, Triebel, Jakob, Schulze-Tanzil, Gundula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997946/
https://www.ncbi.nlm.nih.gov/pubmed/35406699
http://dx.doi.org/10.3390/cells11071134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997946/
https://www.ncbi.nlm.nih.gov/pubmed/35406699
http://dx.doi.org/10.3390/cells11071134

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