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Better Outcomes with Intranigral versus Intrastriatal Cell Transplantation: Relevance for Parkinson’s Disease

Intrastriatal embryonic ventral mesencephalon grafts have been shown to integrate, survive, and reinnervate the host striatum in clinical settings and in animal models of Parkinson’s disease. However, this ectopic location does not restore the physiological loops of the nigrostriatal pathway and pro...

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Detalles Bibliográficos
Autores principales: Droguerre, Marine, Brot, Sébastien, Vitrac, Clément, Benoit-Marand, Marianne, Belnoue, Laure, Patrigeon, Maelig, Lainé, Anaïs, Béré, Emile, Jaber, Mohamed, Gaillard, Afsaneh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997951/
https://www.ncbi.nlm.nih.gov/pubmed/35406755
http://dx.doi.org/10.3390/cells11071191