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Src-Family Protein Kinase Inhibitors Suppress MYB Activity in a p300-Dependent Manner

Recent studies have disclosed transcription factor MYB as a potential drug target for malignancies that are dependent on deregulated MYB function, including acute myeloid leukemia (AML) and adenoid cystic carcinoma (ACC). Although transcription factors are often regarded as undruggable, successful t...

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Detalles Bibliográficos
Autores principales: Biyanee, Abhiruchi, Yusenko, Maria V., Klempnauer, Karl-Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997952/
https://www.ncbi.nlm.nih.gov/pubmed/35406726
http://dx.doi.org/10.3390/cells11071162