Activin A Causes Muscle Atrophy through MEF2C-Dependent Impaired Myogenesis

Activin A (ActA) is considered to play a major role in cancer-induced cachexia (CC). Indeed, circulating ActA levels are elevated and predict survival in patients with CC. However, the mechanisms by which ActA mediates CC development and in particular skeletal muscle (SM) atrophy in humans are not y...

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Detalles Bibliográficos
Autores principales: Loumaye, Audrey, Lause, Pascale, Zhong, Xiaoling, Zimmers, Teresa A., Bindels, Laure B., Thissen, Jean-Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997966/
https://www.ncbi.nlm.nih.gov/pubmed/35406681
http://dx.doi.org/10.3390/cells11071119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997966/
https://www.ncbi.nlm.nih.gov/pubmed/35406681
http://dx.doi.org/10.3390/cells11071119

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