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Activin A Causes Muscle Atrophy through MEF2C-Dependent Impaired Myogenesis
Activin A (ActA) is considered to play a major role in cancer-induced cachexia (CC). Indeed, circulating ActA levels are elevated and predict survival in patients with CC. However, the mechanisms by which ActA mediates CC development and in particular skeletal muscle (SM) atrophy in humans are not y...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997966/ https://www.ncbi.nlm.nih.gov/pubmed/35406681 http://dx.doi.org/10.3390/cells11071119 |