L-Type Ca(v)1.3 Calcium Channels Are Required for Beta-Adrenergic Triggered Automaticity in Dormant Mouse Sinoatrial Pacemaker Cells

Background: Sinoatrial node cells (SANC) automaticity is generated by functional association between the activity of plasmalemmal ion channels and local diastolic intracellular Ca(2+) release (LCR) from ryanodine receptors. Strikingly, most isolated SANC exhibit a “dormant” state, whereas only a fra...

Descripción completa

Detalles Bibliográficos
Autores principales: Louradour, Julien, Bortolotti, Olivier, Torre, Eleonora, Bidaud, Isabelle, Lamb, Ned, Fernandez, Anne, Le Guennec, Jean-Yves, Mangoni, Matteo E., Mesirca, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997967/
https://www.ncbi.nlm.nih.gov/pubmed/35406677
http://dx.doi.org/10.3390/cells11071114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8997967/
https://www.ncbi.nlm.nih.gov/pubmed/35406677
http://dx.doi.org/10.3390/cells11071114

Ejemplares similares