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In Vitro Characterization of Doxorubicin-Mediated Stress-Induced Premature Senescence in Human Chondrocytes

Accumulation of senescent chondrocytes is thought to drive inflammatory processes and subsequent cartilage degeneration in age-related as well as posttraumatic osteoarthritis (OA). However, the underlying mechanisms of senescence and consequences on cartilage homeostasis are not completely understoo...

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Detalles Bibliográficos
Autores principales: Kirsch, Valeria, Ramge, Jan-Moritz, Schoppa, Astrid, Ignatius, Anita, Riegger, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998002/
https://www.ncbi.nlm.nih.gov/pubmed/35406671
http://dx.doi.org/10.3390/cells11071106