Identification of Transcription Factors Responsible for a Transforming Growth Factor-β-Driven Hypertrophy-like Phenotype in Human Osteoarthritic Chondrocytes

During osteoarthritis (OA), hypertrophy-like chondrocytes contribute to the disease process. TGF-β’s signaling pathways can contribute to a hypertrophy(-like) phenotype in chondrocytes, especially at high doses of TGF-β. In this study, we examine which transcription factors (TFs) are activated and i...

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Detalles Bibliográficos
Autores principales: Thielen, Nathalie G. M., Neefjes, Margot, Vitters, Elly L., van Beuningen, Henk M., Blom, Arjen B., Koenders, Marije I., van Lent, Peter L. E. M., van de Loo, Fons A. J., Blaney Davidson, Esmeralda N., van Caam, Arjan P. M., van der Kraan, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998018/
https://www.ncbi.nlm.nih.gov/pubmed/35406794
http://dx.doi.org/10.3390/cells11071232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998018/
https://www.ncbi.nlm.nih.gov/pubmed/35406794
http://dx.doi.org/10.3390/cells11071232

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