A Boronated Derivative of Temozolomide Showing Enhanced Efficacy in Boron Neutron Capture Therapy of Glioblastoma

There is an incontestable need for improved treatment modality for glioblastoma due to its extraordinary resistance to traditional chemoradiation therapy. Boron neutron capture therapy (BNCT) may play a role in the future. We designed and synthesized a (10)B-boronated derivative of temozolomide, TMZ...

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Detalles Bibliográficos
Autores principales: Xiang, Jing, Ma, Lin, Gu, Zheng, Jin, Hongjun, Zhai, Hongbin, Tong, Jianfei, Liang, Tianjiao, Li, Juan, Ren, Qiushi, Liu, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998031/
https://www.ncbi.nlm.nih.gov/pubmed/35406737
http://dx.doi.org/10.3390/cells11071173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998031/
https://www.ncbi.nlm.nih.gov/pubmed/35406737
http://dx.doi.org/10.3390/cells11071173

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