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Protective Effects of Growth Differentiation Factor-6 on the Intervertebral Disc: An In Vitro and In Vivo Study

Growth differentiation factors (GDFs) regulate homeostasis by amplifying extracellular matrix anabolism and inhibiting pro-inflammatory cytokine production in the intervertebral disc (IVD). The aim of this study was to elucidate the effects of GDF-6 on human IVD nucleus pulposus (NP) cells using a t...

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Detalles Bibliográficos
Autores principales: Miyazaki, Kunihiko, Miyazaki, Shingo, Yurube, Takashi, Takeoka, Yoshiki, Kanda, Yutaro, Zhang, Zhongying, Kakiuchi, Yuji, Tsujimoto, Ryu, Ohnishi, Hiroki, Matsuo, Tomoya, Ryu, Masao, Kuroda, Ryosuke, Kakutani, Kenichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998060/
https://www.ncbi.nlm.nih.gov/pubmed/35406739
http://dx.doi.org/10.3390/cells11071174