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Protective Effects of Growth Differentiation Factor-6 on the Intervertebral Disc: An In Vitro and In Vivo Study
Growth differentiation factors (GDFs) regulate homeostasis by amplifying extracellular matrix anabolism and inhibiting pro-inflammatory cytokine production in the intervertebral disc (IVD). The aim of this study was to elucidate the effects of GDF-6 on human IVD nucleus pulposus (NP) cells using a t...
Autores principales: | Miyazaki, Kunihiko, Miyazaki, Shingo, Yurube, Takashi, Takeoka, Yoshiki, Kanda, Yutaro, Zhang, Zhongying, Kakiuchi, Yuji, Tsujimoto, Ryu, Ohnishi, Hiroki, Matsuo, Tomoya, Ryu, Masao, Kuroda, Ryosuke, Kakutani, Kenichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998060/ https://www.ncbi.nlm.nih.gov/pubmed/35406739 http://dx.doi.org/10.3390/cells11071174 |
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