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Oxidative Stress-Induced TRPV2 Expression Increase Is Involved in Diabetic Cataracts and Apoptosis of Lens Epithelial Cells in a High-Glucose Environment

Cataracts are a serious complication of diabetes. In long-term hyperglycemia, intracellular Ca(2+) concentration ([Ca(2+)](i)) and reactive oxygen species (ROS) are increased. The apoptosis of lens epithelial cells plays a key role in the development of cataract. We investigated a potential role for...

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Detalles Bibliográficos
Autores principales: Chen, Linghui, Chen, Yanzhuo, Ding, Wen, Zhan, Tao, Zhu, Jie, Zhang, Lesha, Wang, Han, Shen, Bing, Wang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998065/
https://www.ncbi.nlm.nih.gov/pubmed/35406761
http://dx.doi.org/10.3390/cells11071196