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Isolation of Neoantigen-Specific Human T Cell Receptors from Different Human and Murine Repertoires
SIMPLE SUMMARY: T cell-based immunotherapy has achieved remarkable clinical responses in patients with cancer. Neoepitope-specific T cells can specifically recognize mutated tumor cells and have led to tumor regression in mouse models and clinical studies. However, isolating neoepitope-specific T ce...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998067/ https://www.ncbi.nlm.nih.gov/pubmed/35406613 http://dx.doi.org/10.3390/cancers14071842 |