Cargando…

Isolation of Neoantigen-Specific Human T Cell Receptors from Different Human and Murine Repertoires

SIMPLE SUMMARY: T cell-based immunotherapy has achieved remarkable clinical responses in patients with cancer. Neoepitope-specific T cells can specifically recognize mutated tumor cells and have led to tumor regression in mouse models and clinical studies. However, isolating neoepitope-specific T ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Grunert, Corinna, Willimsky, Gerald, Peuker, Caroline Anna, Rhein, Simone, Hansmann, Leo, Blankenstein, Thomas, Blanc, Eric, Beule, Dieter, Keller, Ulrich, Pezzutto, Antonio, Busse, Antonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998067/
https://www.ncbi.nlm.nih.gov/pubmed/35406613
http://dx.doi.org/10.3390/cancers14071842