GLP-1 Mediates Regulation of Colonic ACE2 Expression by the Bile Acid Receptor GPBAR1 in Inflammation

Background & Aims: ACE2, a carboxypeptidase that generates Ang-(1-7) from Ang II, is highly expressed in the lung, small intestine and colon. GPBAR1, is a G protein bile acid receptor that promotes the release of the insulinotropic factor glucagon-like peptide (GLP)-1 and attenuates intestinal i...

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Detalles Bibliográficos
Autores principales: Biagioli, Michele, Marchianò, Silvia, Roselli, Rosalinda, Di Giorgio, Cristina, Bellini, Rachele, Bordoni, Martina, Distrutti, Eleonora, Catalanotti, Bruno, Zampella, Angela, Graziosi, Luigina, Donini, Annibale, Fiorucci, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998127/
https://www.ncbi.nlm.nih.gov/pubmed/35406751
http://dx.doi.org/10.3390/cells11071187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998127/
https://www.ncbi.nlm.nih.gov/pubmed/35406751
http://dx.doi.org/10.3390/cells11071187

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