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Mechanistic Insight into the Mode of Action of Acid β-Glucosidase Enhancer Ambroxol

Ambroxol (ABX) is a mucolytic agent used for the treatment of respiratory diseases. Bioactivity has been demonstrated as an enhancement effect on lysosomal acid β-glucosidase (β-Glu) activity in Gaucher disease (GD). The positive effects observed have been attributed to a mechanism of action similar...

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Detalles Bibliográficos
Autores principales: Pantoom, Supansa, Hules, Larissa, Schöll, Christopher, Petrosyan, Andranik, Monticelli, Maria, Pospech, Jola, Cubellis, Maria Vittoria, Hermann, Andreas, Lukas, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998264/
https://www.ncbi.nlm.nih.gov/pubmed/35408914
http://dx.doi.org/10.3390/ijms23073536