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Combination Strategy of Genetic Dereplication and Manipulation of Epigenetic Regulators Reveals a Novel Compound from Plant Endophytic Fungus

The strategies of genetic dereplication and manipulation of epigenetic regulators to activate the cryptic gene clusters are effective to discover natural products with novel structure in filamentous fungi. In this study, a combination of genetic dereplication (deletion of pesthetic acid biosynthetic...

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Detalles Bibliográficos
Autores principales: Yang, Lu, Wu, Guangwei, Meng, Fanyue, Ran, Huomiao, Yin, Wenbing, Li, Wei, Liu, Xiaoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998291/
https://www.ncbi.nlm.nih.gov/pubmed/35409046
http://dx.doi.org/10.3390/ijms23073686