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The Evidence for Effective Inhibition of I(Na) Produced by Mirogabalin ((1R,5S,6S)-6-(aminomethyl)-3-ethyl-bicyclo [3.2.0] hept-3-ene-6-acetic acid), a Known Blocker of Ca(V) Channels
Mirogabalin (MGB, Tarlige(®)), an inhibitor of the α(2)δ-1 subunit of voltage-gated Ca(2+) (Ca(V)) channels, is used as a way to alleviate peripheral neuropathic pain and diabetic neuropathy. However, to what extent MGB modifies the magnitude, gating, and/or hysteresis of various types of plasmalemm...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998350/ https://www.ncbi.nlm.nih.gov/pubmed/35409204 http://dx.doi.org/10.3390/ijms23073845 |