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Diversity-Oriented Synthesis Catalyzed by Diethylaminosulfur-Trifluoride—Preparation of New Antitumor Ecdysteroid Derivatives

Fluorine represents a privileged building block in pharmaceutical chemistry. Diethylaminosulfur-trifluoride (DAST) is a reagent commonly used for replacement of alcoholic hydroxyl groups with fluorine and is also known to catalyze water elimination and cyclic Beckmann-rearrangement type reactions. I...

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Detalles Bibliográficos
Autores principales: Vágvölgyi, Máté, Kocsis, Endre, Nové, Márta, Szemerédi, Nikoletta, Spengler, Gabriella, Kele, Zoltán, Berkecz, Róbert, Gáti, Tamás, Tóth, Gábor, Hunyadi, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998355/
https://www.ncbi.nlm.nih.gov/pubmed/35408806
http://dx.doi.org/10.3390/ijms23073447