Proteomic Analysis of Methylglyoxal Modifications Reveals Susceptibility of Glycolytic Enzymes to Dicarbonyl Stress

Methylglyoxal (MGO) is a highly reactive cellular metabolite that glycates lysine and arginine residues to form post-translational modifications known as advanced glycation end products. Because of their low abundance and low stoichiometry, few studies have reported their occurrence and site-specifi...

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Detalles Bibliográficos
Autores principales: Donnellan, Leigh, Young, Clifford, Simpson, Bradley S., Acland, Mitchell, Dhillon, Varinderpal S., Costabile, Maurizio, Fenech, Michael, Hoffmann, Peter, Deo, Permal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998448/
https://www.ncbi.nlm.nih.gov/pubmed/35409048
http://dx.doi.org/10.3390/ijms23073689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998448/
https://www.ncbi.nlm.nih.gov/pubmed/35409048
http://dx.doi.org/10.3390/ijms23073689

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