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Free L-Lysine and Its Methyl Ester React with Glyoxal and Methylglyoxal in Phosphate Buffer (100 mM, pH 7.4) to Form N(ε)-Carboxymethyl-Lysine, N(ε)-Carboxyethyl-Lysine and N(ε)-Hydroxymethyl-Lysine

Glyoxal (GO) and methylglyoxal (MGO) are highly reactive species formed in carbohydrate metabolism. N(ε)-Carboxymethyllysine (CML) and N(ε)-carboxyethyllysine (CEL) are considered to be the advanced glycation end-products (AGEs) of L-lysine (Lys) with GO and MGO, respectively. Here, we investigated...

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Detalles Bibliográficos
Autores principales: Baskal, Svetlana, Tsikas, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998464/
https://www.ncbi.nlm.nih.gov/pubmed/35408807
http://dx.doi.org/10.3390/ijms23073446