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Free L-Lysine and Its Methyl Ester React with Glyoxal and Methylglyoxal in Phosphate Buffer (100 mM, pH 7.4) to Form N(ε)-Carboxymethyl-Lysine, N(ε)-Carboxyethyl-Lysine and N(ε)-Hydroxymethyl-Lysine
Glyoxal (GO) and methylglyoxal (MGO) are highly reactive species formed in carbohydrate metabolism. N(ε)-Carboxymethyllysine (CML) and N(ε)-carboxyethyllysine (CEL) are considered to be the advanced glycation end-products (AGEs) of L-lysine (Lys) with GO and MGO, respectively. Here, we investigated...
Autores principales: | Baskal, Svetlana, Tsikas, Dimitrios |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998464/ https://www.ncbi.nlm.nih.gov/pubmed/35408807 http://dx.doi.org/10.3390/ijms23073446 |
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