Cargando…

The Effect of CFTR Modulators on Airway Infection in Cystic Fibrosis

The advent of Cystic fibrosis transmembrane receptor (CFTR) modulators in 2012 was a critical event in the history of cystic fibrosis (CF) treatment. Unlike traditional therapies that target downstream effects of CFTR dysfunction, CFTR modulators aim to correct the underlying defect at the protein l...

Descripción completa

Detalles Bibliográficos
Autores principales:	Harvey, Caitlyn, Weldon, Sinead, Elborn, Stuart, Downey, Damian G., Taggart, Clifford
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998472/ https://www.ncbi.nlm.nih.gov/pubmed/35408875 http://dx.doi.org/10.3390/ijms23073513

Ejemplares similares

Airway Inflammation and Host Responses in the Era of CFTR Modulators
por: Keown, Karen, et al.
Publicado: (2020)

Targeted therapies to improve CFTR function in cystic fibrosis
por: Brodlie, Malcolm, et al.
Publicado: (2015)

CFTR Modulator Therapies: Potential Impact on Airway Infections in Cystic Fibrosis
por: Saluzzo, Francesca, et al.
Publicado: (2022)

Antiproteases as Therapeutics to Target Inflammation in Cystic Fibrosis
por: Quinn, Derek J, et al.
Publicado: (2010)

Changes in the Cystic Fibrosis Airway Microbiome in Response to CFTR Modulator Therapy
por: Yi, Buqing, et al.
Publicado: (2021)

The Role of Serine Proteases and Antiproteases in the Cystic Fibrosis Lung
por: Twigg, Matthew S., et al.
Publicado: (2015)

Coinfection with Pseudomonas aeruginosa and Aspergillus fumigatus in cystic fibrosis
por: Keown, Karen, et al.
Publicado: (2020)

CFTR modulators: transformative therapies for cystic fibrosis
por: Dwight, Mary, et al.
Publicado: (2021)

Modulator treatment for people with cystic fibrosis: moving in the right direction
por: Elborn, J. Stuart
Publicado: (2020)

Mutual Effects of Single and Combined CFTR Modulators and Bacterial Infection in Cystic Fibrosis
por: Cigana, Cristina, et al.
Publicado: (2023)

The effect of CFTR modulators on structural lung disease in cystic fibrosis
por: Mok, L. Clara, et al.
Publicado: (2023)

MRSA eradication of newly acquired lower respiratory tract infection in cystic fibrosis
por: Vallières, Emilie, et al.
Publicado: (2016)

Timing of hypertonic saline and airway clearance techniques in adults with cystic fibrosis during pulmonary exacerbation: pilot data from a randomised crossover study
por: O'Neill, Katherine, et al.
Publicado: (2017)

Lived experiences of individuals with cystic fibrosis on CFTR-modulators
por: Page, Annelise, et al.
Publicado: (2022)

Nutritional impact of CFTR modulators in children with cystic fibrosis
por: Gaschignard, Margaux, et al.
Publicado: (2023)

Cystic fibrosis gene modifier SLC26A9 modulates airway response to CFTR-directed therapeutics
por: Strug, Lisa J., et al.
Publicado: (2016)

Effects of CFTR modulators on serum biomarkers of liver fibrosis in children with cystic fibrosis
por: Levitte, Steven, et al.
Publicado: (2023)

CFTR modulator therapies – Effect on life expectancy in people with cystic fibrosis
por: Balfour-Lynn, I.M., et al.
Publicado: (2022)

Long-term effectiveness of dual CFTR modulator treatment of cystic fibrosis
por: Muilwijk, Danya, et al.
Publicado: (2022)

Lung function and disease severity in cystic fibrosis patients heterozygous for p.Arg117His
por: Shteinberg, Michal, et al.
Publicado: (2017)

STAPHYLOCOCCUS AUREUS ENTEROTOXINS IN PEOPLE WITH CYSTIC FIBROSIS (CF)
por: Wen, Hongjie, et al.
Publicado: (2020)

Role of inhaled antibiotics in the era of highly effective CFTR modulators
por: Elborn, J. Stuart, et al.
Publicado: (2023)

CFTR Modulators: Shedding Light on Precision Medicine for Cystic Fibrosis
por: Lopes-Pacheco, Miquéias
Publicado: (2016)

Triplet CFTR modulators: future prospects for treatment of cystic fibrosis
por: Chaudary, Nauman
Publicado: (2018)

Cystic fibrosis transmembrane conductance regulator (CFTR) modulators have differential effects on cystic fibrosis macrophage function
por: Zhang, Shuzhong, et al.
Publicado: (2018)

Airway microbial diversity is decreased in young children with cystic fibrosis compared to healthy controls but improved with CFTR modulation
por: Hahn, Andrea, et al.
Publicado: (2020)

Cystic Fibrosis, CFTR, and Colorectal Cancer
por: Scott, Patricia, et al.
Publicado: (2020)

Antisense oligonucleotide eluforsen improves CFTR function in F508del cystic fibrosis
por: Sermet-Gaudelus, Isabelle, et al.
Publicado: (2018)

Ciprofloxacin dry powder inhaler in cystic fibrosis
por: Elborn, J Stuart
Publicado: (2016)

CFTR targeted therapies: recent advances in cystic fibrosis and possibilities in other diseases of the airways
por: Patel, Sheylan D., et al.
Publicado: (2020)

TACKLING ANTIMICROBIAL RESISTANCE (AMR) - IN VITRO EFFECT OF SODIUM CHLORIDE ON ANTIBIOTIC SUSCEPTIBILITY IN CLINICAL PSEUDOMONAS AERUGINOSA ISOLATED FROM PATIENTS WITH CYSTIC FIBROSIS (CF)
por: Gramegna, Andrea, et al.
Publicado: (2020)

Advancing clinical development pathways for new CFTR modulators in cystic fibrosis
por: Mayer-Hamblett, Nicole, et al.
Publicado: (2016)

CFTR Modulators: Impact on Fertility, Pregnancy, and Lactation in Women with Cystic Fibrosis
por: Taylor-Cousar, Jennifer L.
Publicado: (2020)

Different CFTR modulator combinations downregulate inflammation differently in cystic fibrosis
por: Jarosz-Griffiths, Heledd H, et al.
Publicado: (2020)

CFTR Modulators: The Changing Face of Cystic Fibrosis in the Era of Precision Medicine
por: Lopes-Pacheco, Miquéias
Publicado: (2020)

CFTR Modulators to the Rescue of Individuals with Cystic Fibrosis and Advanced Lung Disease
por: Myerburg, Mike, et al.
Publicado: (2021)

CFTR Modulator Therapy and Its Impact on Lung Transplantation in Cystic Fibrosis
por: Benden, Christian, et al.
Publicado: (2021)

Validation of nasospheroids to assay CFTR functionality and modulator responses in cystic fibrosis
por: Calucho, Maite, et al.
Publicado: (2021)

Therapeutic Approaches for Patients with Cystic Fibrosis Not Eligible for Current CFTR Modulators
por: Fajac, Isabelle, et al.
Publicado: (2021)

CFTR Modulators in People with Cystic Fibrosis: Real-World Evidence in France
por: Regard, Lucile, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_8amog2ajmaohtgmjvq3mrbpef6