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Optimization and Validation of Dosage Regimen for Ceftiofur against Pasteurella multocida in Swine by Physiological Based Pharmacokinetic–Pharmacodynamic Model

Model informed drug development is a valuable tool for drug development and clinical application due to its ability to integrate variability and uncertainty of data. This study aimed to determine an optimal dosage of ceftiofur against P. multocida by ex vivo pharmacokinetic/pharmacodynamic (PK/PD) m...

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Detalles Bibliográficos
Autores principales: Mi, Kun, Pu, Shanju, Hou, Yixuan, Sun, Lei, Zhou, Kaixiang, Ma, Wenjin, Xu, Xiangyue, Huo, Meixia, Liu, Zhenli, Xie, Changqing, Qu, Wei, Huang, Lingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998519/
https://www.ncbi.nlm.nih.gov/pubmed/35409082
http://dx.doi.org/10.3390/ijms23073722