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Optimization and Validation of Dosage Regimen for Ceftiofur against Pasteurella multocida in Swine by Physiological Based Pharmacokinetic–Pharmacodynamic Model
Model informed drug development is a valuable tool for drug development and clinical application due to its ability to integrate variability and uncertainty of data. This study aimed to determine an optimal dosage of ceftiofur against P. multocida by ex vivo pharmacokinetic/pharmacodynamic (PK/PD) m...
Autores principales: | Mi, Kun, Pu, Shanju, Hou, Yixuan, Sun, Lei, Zhou, Kaixiang, Ma, Wenjin, Xu, Xiangyue, Huo, Meixia, Liu, Zhenli, Xie, Changqing, Qu, Wei, Huang, Lingli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998519/ https://www.ncbi.nlm.nih.gov/pubmed/35409082 http://dx.doi.org/10.3390/ijms23073722 |
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