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The Merkel Cell Polyomavirus T-Antigens and IL-33/ST2-IL1RAcP Axis: Possible Role in Merkel Cell Carcinoma

Merkel cell polyomavirus (MCPyV) is a causal factor in Merkel cell carcinoma (MCC). The oncogenic potential is mediated through its viral oncoproteins large T-antigen (LT) and small T-antigen (sT). Cytokines produced by tumor cells play an important role in cancer pathogenesis, and viruses affect th...

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Detalles Bibliográficos
Autores principales: Rasheed, Kashif, Moens, Ugo, Policastro, Benedetta, Johnsen, John Inge, Koljonen, Virve, Sihto, Harri, Lui, Weng-Onn, Sveinbjørnsson, Baldur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998536/
https://www.ncbi.nlm.nih.gov/pubmed/35409061
http://dx.doi.org/10.3390/ijms23073702