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HDAC Inhibitor Sodium Butyrate Attenuates the DNA Repair in Transformed but Not in Normal Fibroblasts

Many cancer therapy strategies cause DNA damage leading to the death of tumor cells. The DNA damage response (DDR) modulators are considered as promising candidates for use in combination therapy to enhance the efficacy of DNA-damage-mediated cancer treatment. The inhibitors of histone deacetylases...

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Detalles Bibliográficos
Autores principales: Gnedina, Olga O., Morshneva, Alisa V., Skvortsova, Elena V., Igotti, Maria V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998589/
https://www.ncbi.nlm.nih.gov/pubmed/35408878
http://dx.doi.org/10.3390/ijms23073517