Phosphorylation but Not Oligomerization Drives the Accumulation of Tau with Nucleoporin Nup98

Tau is a neuronal protein that stabilizes axonal microtubules (MTs) in the central nervous system. In Alzheimer’s disease (AD) and other tauopathies, phosphorylated Tau accumulates in intracellular aggregates, a pathological hallmark of these diseases. However, the chronological order of pathologica...

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Detalles Bibliográficos
Autores principales: Diez, Lisa, Kapinos, Larisa E., Hochmair, Janine, Huebschmann, Sabrina, Dominguez-Baquero, Alvaro, Vogt, Amelie, Rankovic, Marija, Zweckstetter, Markus, Lim, Roderick Y. H., Wegmann, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998617/
https://www.ncbi.nlm.nih.gov/pubmed/35408855
http://dx.doi.org/10.3390/ijms23073495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998617/
https://www.ncbi.nlm.nih.gov/pubmed/35408855
http://dx.doi.org/10.3390/ijms23073495

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