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Phosphorylation but Not Oligomerization Drives the Accumulation of Tau with Nucleoporin Nup98
Tau is a neuronal protein that stabilizes axonal microtubules (MTs) in the central nervous system. In Alzheimer’s disease (AD) and other tauopathies, phosphorylated Tau accumulates in intracellular aggregates, a pathological hallmark of these diseases. However, the chronological order of pathologica...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8998617/ https://www.ncbi.nlm.nih.gov/pubmed/35408855 http://dx.doi.org/10.3390/ijms23073495 |